International Textbook of Leprosy

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Leprosy is a curable infectious disease. The causative agent, Mycobacterium leprae, has the unique capability to infect peripheral nerves, which may lead to varying degrees of neuropathy. In the most severe circumstances, this infection may result in an inability to feel pain in the hands or feet, a loss of digits, and blindness

Paradoxically, as treatment has become more successful, many specialized centers have closed and few physicians have adequate knowledge about the disease. A strong stigma, based on fear, still contributes to prolonged suffering and delayed diagnosis. Today, the diagnosis and treatment of leprosy also is often impeded by a lack of knowledge and awareness in the healthcare community. This textbook attempts to address the deficiency

The International Textbook of Leprosy is dedicated to the physicians and health workers caring for their first patient with leprosy, and to all of those in the research community who have encountered some of the fascinating scientific aspects of leprosy and wish to learn more.

— David M Scollard and Thomas P Gillis, Editors


Citation

Scollard, DM, & Gillis, TP, Eds. (2016) International Textbook of Leprosy. American Leprosy Missions, Greenville, SC. https://doi.org/10.1489/itl

Explore articles

CLINICAL SCIENCE

  1. Epidemiology
    1. Epidemiology of Leprosy(JH Richardus, E Ignotti, WCS Smith )
    2. Leprosy Control(JH Richardus, D Pahan, RC Johnson, WCS Smith )
  2. Clinical Aspects
    1. Clinical Diagnosis of Leprosy( JH Richardus, E Ignotti, WCS Smith )
    2. Leprosy Reactions( SL Walker )
    3. Differential Diagnosis of Leprosy(SL Moschella, V Garcia Albea )
    4. Pathogenesis and Pathology of Leprosy(DM Scollard)
    5. Neurological Manifestations of Leprosy(J Vijayan, EP Wilder-Smith)
    6. Treatment of Leprosy(DN Lockwood)

BASIC SCIENCE

  1. Microbiology
    1. The Physiology of Mycobacterium leprae(PJ Brennan,JS Spencer )
    2. Anti-Leprosy Drugs: Modes of Action and Mechanisms of Resistance in Mycobacterium leprae(E Cambau,DL Williams )
    3. Cultivation and Viability Determination of Mycobacterium leprae(R Lahiri, LB Adams)
  2. Immunology
    1. Innate Immunity(MO Moraes, LRB Silva,RO Pinheiro )
    2. Adaptive Immune Response in Leprosy(MO Moraes,LRB Silva , RO Pinheiro)
    3. Vaccines for Prevention of Leprosy(SG Reed,MS Duthie )